Giulianotti, Marc A. : rechercher sur Z-Library

Le plus grand référentiel d'articles scientifiques au monde. 70,000,000+ d'articles gratuitement.

Don't use scam websites

Livres
Articles (88)
Les plus populaires
Liste
- Liste
- Tableau

1

Shifting from the single to the multitarget paradigm in drug discovery

Medina-Franco, José L., Giulianotti, Marc A., Welmaker, Gregory S., Houghten, Richard A.

Journal:

Drug Discovery Today

Année:

2013

Langue:

english

Fichier:

PDF, 1.03 MB

english, 2013

2

Book reviews

Green, Barbara Pinto, Crawford, Scott A.G.M., Richards, Jeffrey, Crawford, Marc A., Williams, Chris, Nash, Rex, Hill, Jeffrey, Giulianotti, Richard, Stein, Julian U., Kozar, Andy, Carroll, John M., Wi

Journal:

International Journal of the History of Sport

Année:

2000

Langue:

english

Fichier:

PDF, 2.66 MB

english, 2000

3

Tissue Chips in Space: Modeling Human Diseases in Microgravity

Low, Lucie A., Giulianotti, Marc A.

Journal:

Pharmaceutical Research

Année:

2020

Langue:

english

Fichier:

PDF, 760 KB

english, 2020

4

Use and Implications of the Harmonic Mean Model on Mixtures for Basic Research and Drug Discovery

Santos, Radleigh G., Giulianotti, Marc A., Dooley, Colette T., Pinilla, Clemencia, Appel, Jon R., Houghten, Richard A.

Journal:

ACS Combinatorial Science

Année:

2011

Langue:

english

Fichier:

PDF, 2.14 MB

english, 2011

5

Identification of Tetrapeptides from a Mixture Based Positional Scanning Library That Can Restore nM Full Agonist Function of the L106P, I69T, I102S, A219V, C271Y, and C271R Human Melanocortin-4 Polymorphic Receptors (hMC4Rs)

Haslach, Erica M., Huang, Huisuo, Dirain, Marvin, Debevec, Ginamarie, Geer, Phaedra, Santos, Radleigh G., Giulianotti, Marc A., Pinilla, Clemencia, Appel, Jon R., Doering, Skye R., Walters, Michael A.

Journal:

Journal of Medicinal Chemistry

Année:

2014

Langue:

english

Fichier:

PDF, 5.12 MB

english, 2014

6

Discovery of Polypharmacological Melanocortin-3 and -4 Receptor Probes and Identification of a 100-Fold Selective nM MC3R Agonist versus a µM MC4R Partial Agonist

Fleming, Katlyn A., Freeman, Katie T., Powers, Mike D., Santos, Radleigh G., Debevec, Ginamarie, Giulianotti, Marc A., Houghten, Richard A., Doering, Skye R., Pinilla, Clemencia, Haskell-Luevano, Carr

Journal:

Journal of Medicinal Chemistry

Année:

2019

Langue:

english

Fichier:

PDF, 1.21 MB

english, 2019

7

Pharmaceutical Research Enabled Through Microgravity: Perspectives on the Use of the International Space Station U.S. National Laboratory

Giulianotti, Marc A., Low, Lucie A.

Journal:

Pharmaceutical Research

Année:

2020

Langue:

english

Fichier:

PDF, 467 KB

english, 2020

8

Pharmaceutical Research Enabled Through Microgravity: Perspectives on the Use of the International Space Station U.S. National Laboratory

Giulianotti, Marc A., Low, Lucie A.

Journal:

Pharmaceutical Research

Année:

2020

Fichier:

PDF, 467 KB

2020

9

Characterization of a comprehensive flavor database

Karina Martínez-Mayorga, Terry L. Peppard, Austin B. Yongye, Radleigh Santos, Marc Giulianotti, Jose L. Medina-Franco

Journal:

Journal of Chemometrics

Année:

2011

Langue:

english

Fichier:

PDF, 580 KB

english, 2011

10

ChemInform Abstract: A Facile Approach to Polysubstituted Pyrazoles from Hydrazonyl Chlorides and Vinyl Azides.

Hongbin Zou, Huajian Zhu, Jiaan Shao, Jianwei Wu, Wenteng Chen, Marc A. Giulianotti, Yongping Yu

Journal:

Année:

2011

Fichier:

PDF, 33 KB

2011

11

Conformation-opioid activity relationships of bicyclic guanidines from 3D similarity analysis

Karina Martínez-Mayorga, Jose L. Medina-Franco, Marc A. Giulianotti, Clemencia Pinilla, Colette T. Dooley, Jon R. Appel, Richard A. Houghten

Journal:

Bioorganic & Medicinal Chemistry

Année:

2008

Langue:

english

Fichier:

PDF, 423 KB

english, 2008

12

Identification, structure–activity relationships and molecular modeling of potent triamine and piperazine opioid ligands

Austin B. Yongye, Jon R. Appel, Marc A. Giulianotti, Colette T. Dooley, Jose L. Medina-Franco, Adel Nefzi, Richard A. Houghten, Karina Martínez-Mayorga

Journal:

Bioorganic & Medicinal Chemistry

Année:

2009

Langue:

english

Fichier:

PDF, 1.40 MB

english, 2009

13

Towards a systematic characterization of the antiprotozoal activity landscape of benzimidazole derivatives

Jaime Pérez-Villanueva, Radleigh Santos, Alicia Hernández-Campos, Marc A. Giulianotti, Rafael Castillo, Jose L. Medina-Franco

Journal:

Bioorganic & Medicinal Chemistry

Année:

2010

Langue:

english

Fichier:

PDF, 2.03 MB

english, 2010

14

Discovery of a novel protein kinase B inhibitor by structure-based virtual screening

Jose L. Medina-Franco, Marc A. Giulianotti, Yongping Yu, Liangliang Shen, Libo Yao, Narender Singh

Journal:

Bioorganic & Medicinal Chemistry Letters

Année:

2009

Langue:

english

Fichier:

PDF, 347 KB

english, 2009

15

A facile approach to polysubstituted pyrazoles from hydrazonyl chlorides and vinyl azides

Hongbin Zou, Huajian Zhu, Jiaan Shao, Jianwei Wu, Wenteng Chen, Marc A. Giulianotti, Yongping Yu

Journal:

Année:

2011

Langue:

english

Fichier:

PDF, 303 KB

english, 2011

16

High-throughput parallel synthesis of 3,4-disubstituted 1-(ω-hydroxyalkyl) imidazolin-2-ones on ‘volatilizable’ supports

Yangmei Li, Yongping Yu, Marc Giulianotti, Richard A. Houghten

Journal:

Tetrahedron Letters

Année:

2008

Langue:

english

Fichier:

PDF, 90 KB

english, 2008

17

Traceless solid-phase synthesis of N-substituted 3,5-bis(substituted-idene)piperidin-4-one derivatives

Zhang Liu, Jose L. Medina-Franco, Richard A. Houghten, Marc A. Giulianotti

Journal:

Tetrahedron Letters

Année:

2010

Langue:

english

Fichier:

PDF, 166 KB

english, 2010

18

A facile approach to the synthesis of 3,4-disubstituted-2-aminothiazolium derivatives through the use of a ‘volatilizable’ support

Yangmei Li, Marc Giulianotti, Richard A. Houghten

Journal:

Tetrahedron Letters

Année:

2010

Langue:

english

Fichier:

PDF, 190 KB

english, 2010

19

High throughput synthesis of 2,3,6-trisubstituted-5,6-dihydroimidazo[2,1-b]thiazole derivatives

Yangmei Li, Marc Giulianotti, Richard A. Houghten

Journal:

Tetrahedron Letters

Année:

2011

Langue:

english

Fichier:

PDF, 259 KB

english, 2011

20

Solid-phase synthesis of N-substituted 3,4-dihydroquinazolinone derivatives

Zhang Liu, Lili Ou, Marc A. Giulianotti, Richard A. Houghten

Journal:

Tetrahedron Letters

Année:

2011

Langue:

english

Fichier:

PDF, 198 KB

english, 2011

21

Solid-phase synthesis of 2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepine derivatives

Zhang Liu, Wenteng Chen, Marc A. Giulianotti, Richard A. Houghten

Journal:

Tetrahedron Letters

Année:

2011

Langue:

english

Fichier:

PDF, 195 KB

english, 2011

22

Solid-Phase Synthesis of Substituted 2,3-Diketopiperazines from Reduced Polyamides

Adel Nefzi, Marc A. Giulianotti, Richard A. Houghten

Journal:

Année:

2000

Langue:

english

Fichier:

PDF, 151 KB

english, 2000

23

Efficient approach for the diversity-oriented synthesis of macro-heterocycles on solid-support

Marc Giulianotti, Adel Nefzi

Journal:

Tetrahedron Letters

Année:

2003

Langue:

english

Fichier:

PDF, 176 KB

english, 2003

24

Solid phase synthesis of 2,4,5-trisubstituted thiomorpholin-3-ones

Adel Nefzi, Marc Giulianotti, Richard A. Houghten

Journal:

Tetrahedron Letters

Année:

1998

Langue:

english

Fichier:

PDF, 170 KB

english, 1998

25

Solid phase synthesis of 1,4-benzothiazepin-5-one derivatives

Adel Nefzi, Nhi A Ong, Marc A Giulianotti, John M Ostresh, Richard A Houghten

Journal:

Tetrahedron Letters

Année:

1999

Langue:

english

Fichier:

PDF, 199 KB

english, 1999

26

Solid phase synthesis of 1,6-disubstituted 2,3-diketopiperazines and 1,2-disubstituted piperazines from N-acylated amino acids

Adel Nefzi, Marc A. Giulianotti, Richard A. Houghten

Journal:

Tetrahedron Letters

Année:

1999

Langue:

english

Fichier:

PDF, 228 KB

english, 1999

27

Integrating computational and mixture-based screening of combinatorial libraries

Austin B. Yongye, Clemencia Pinilla, Jose L. Medina-Franco, Marc A. Giulianotti, Colette T. Dooley, Jon R. Appel, Adel Nefzi, Thomas Scior, Richard A. Houghten, Karina Martínez-Mayorga

Journal:

Journal of Molecular Modeling

Année:

2011

Langue:

english

Fichier:

PDF, 450 KB

english, 2011

28

Modeling of peptides containing D-amino acids: implications on cyclization

Austin B. Yongye, Yangmei Li, Marc A. Giulianotti, Yongping Yu, Richard A. Houghten, Karina Martínez-Mayorga

Journal:

Journal of Computer-Aided Molecular Design

Année:

2009

Langue:

english

Fichier:

PDF, 721 KB

english, 2009

29

Conformational landscape of platinum(II)-tetraamine complexes: DFT and NBO studies

Austin B. Yongye, Marc A. Giulianotti, Adel Nefzi, Richard A. Houghten, Karina Martínez-Mayorga

Journal:

Journal of Computer-Aided Molecular Design

Année:

2010

Langue:

english

Fichier:

PDF, 659 KB

english, 2010

30

Parallel synthesis of novel antitumor agents: 1,2,3-triazoles bearing biologically active sulfonamide moiety and their 3D-QSAR

Lili Ou, Shuang Han, Wenbo Ding, Ping Jia, Bo Yang, Jose L. Medina-Franco, Marc A. Giulianotti, Jian-Zhong Chen, Yongping Yu

Journal:

Molecular Diversity

Année:

2011

Langue:

english

Fichier:

PDF, 940 KB

english, 2011

31

Potent antimicrobial small molecules screened as inhibitors of tyrosine recombinases and Holliday junction-resolving enzymes

Marc C. Rideout, Jeffrey L. Boldt, Gabriel Vahi-Ferguson, Peter Salamon, Adel Nefzi, John M. Ostresh, Marc Giulianotti, Clemencia Pinilla, Anca M. Segall

Journal:

Molecular Diversity

Année:

2011

Langue:

english

Fichier:

PDF, 930 KB

english, 2011

32

Solid-phase synthesis of 2-alkylidene-6-alkyl-imidazo[2,1-b]thiazole-3,5[2H,6H]-dione derivatives

Yangmei Li, Marc Giulianotti, Richard A. Houghten

Journal:

Tetrahedron Letters

Année:

2009

Langue:

english

Fichier:

PDF, 221 KB

english, 2009

33

Solid-phase synthesis of branched thiohydantoin benzimidazolinethiones and branched thiohydantoin tetrahydroquinoxalinediones

Adel Nefzi, Marc A Giulianotti, Richard A Houghten

Journal:

Tetrahedron Letters

Année:

2000

Langue:

english

Fichier:

PDF, 212 KB

english, 2000

34

Efficient solid phase synthesis of 3,5-disubstituted hydantoins

Adel Nefzi, John M. Ostresh, Marc Giulianotti, Richard A. Houghten

Journal:

Tetrahedron Letters

Année:

1998

Langue:

english

Fichier:

PDF, 170 KB

english, 1998

35

A Similarity-based Data-fusion Approach to the Visual Characterization and Comparison of Compound Databases

José L. Medina-Franco, Gerald M. Maggiora, Marc A. Giulianotti, Clemencia Pinilla, Richard A. Houghten

Journal:

Chemical Biology & Drug Design

Année:

2007

Langue:

english

Fichier:

PDF, 1.40 MB

english, 2007

36

Docking of Protein Kinase B Inhibitors: Implications in the Structure-Based Optimization of a Novel Scaffold

Alicia Hernández-Campos, Israel Velázquez-Martínez, Rafael Castillo, Fabian López-Vallejo, Ping Jia, Yongping Yu, Marc A. Giulianotti, Jose L. Medina-Franco

Journal:

Chemical Biology & Drug Design

Année:

2010

Langue:

english

Fichier:

PDF, 846 KB

english, 2010

37

Identification of Two Novel, Potent, Low-Liability Antinociceptive Compounds from the DirectIn VivoScreening of a Large Mixture-Based Combinatorial Library

Kate J. Reilley, Marc Giulianotti, Colette T. Dooley, Adel Nefzi, Jay P. McLaughlin, Richard A. Houghten

Journal:

The AAPS Journal

Année:

2010

Langue:

english

Fichier:

PDF, 614 KB

english, 2010

38

ChemInform Abstract: Synthesis and Biological Evaluation of 2-Indolinone Derivatives as Potential Antitumor Agents.

Hongbin Zou, Liang Zhang, Jingfeng Ouyang, Marc A. Giulianotti, Yongping Yu

Journal:

Année:

2012

Fichier:

PDF, 31 KB

2012

39

ChemInform Abstract: Solid-Phase Synthesis of Heterocycles from Peptides and Amino Acids.

Zhi Li, Marc Giulianotti, Wenteng Chen, Richard A. Houghten, Yongping Yu

Journal:

Année:

2012

Fichier:

PDF, 18 KB

2012

40

ChemInform Abstract: Synthesis of 2,3,4-Trisubstituted Pyrroles via a Facile Reaction of Vinyl Azides and Tosylmethyl Isocyanide.

Wenteng Chen, Jiaan Shao, Zhi Li, Marc A. Giulianotti, Yongping Yu

Journal:

Année:

2012

Fichier:

PDF, 31 KB

2012

41

Expanding the medicinally relevant chemical space with compound libraries

Fabian López-Vallejo, Marc A. Giulianotti, Richard A. Houghten, José L. Medina-Franco

Journal:

Drug Discovery Today

Année:

2012

Langue:

english

Fichier:

PDF, 1.44 MB

english, 2012

42

Synthesis and biological evaluation of 2-indolinone derivatives as potential antitumor agents

Hongbin Zou, Liang Zhang, Jingfeng Ouyang, Marc A. Giulianotti, Yongping Yu

Journal:

European Journal of Medicinal Chemistry

Année:

2011

Langue:

english

Fichier:

PDF, 835 KB

english, 2011

43

Combining positional scanning peptide libraries, HLA-DR transfectants and bioinformatics to dissect the epitope spectrum of HLA class II cross-restricted CD4+ T cell clones

Mireia Sospedra, Yingdong Zhao, Marc Giulianotti, Richard Simon, Clemencia Pinilla, Roland Martin

Journal:

Journal of Immunological Methods

Année:

2010

Langue:

english

Fichier:

PDF, 725 KB

english, 2010

44

A Novel Method for the Determination of Isokinetic Ratios and Its Application in the Synthesis of Two New Positional Scanning Libraries

Giulianotti, Marc A., Debevec, Ginamarie, Santos, Radleigh G., Maida, Laura E., Chen, Wenteng, Ou, Lili, Yu, Yongping, Dooley, Colette T., Houghten, Richard A.

Journal:

ACS Combinatorial Science

Année:

2012

Langue:

english

Fichier:

PDF, 3.38 MB

english, 2012

45

Fluorescent Mu Selective Opioid Ligands from a Mixture Based Cyclic Peptide Library

Li, Yangmei, Dooley, Colette T., Misler, Jaime A., Debevec, Ginamarie, Giulianotti, Marc A., Cazares, Margaret E., Maida, Laura, Houghten, Richard A.

Journal:

ACS Combinatorial Science

Année:

2012

Langue:

english

Fichier:

PDF, 2.04 MB

english, 2012

46

Strategies for the Use of Mixture-Based Synthetic Combinatorial Libraries: Scaffold Ranking, Direct Testing In Vivo, and Enhanced Deconvolution by Computational Methods

Houghten, Richard A., Pinilla, Clemencia, Giulianotti, Marc A., Appel, Jon R., Dooley, Colette T., Nefzi, Adel, Ostresh, John M., Yu, Yongping, Maggiora, Gerald M., Medina-Franco, Jose L., Brunner, Da

Journal:

Journal of Combinatorial Chemistry

Année:

2008

Langue:

english

Fichier:

PDF, 1.83 MB

english, 2008

47

Novel T cell driven approach leads to the identification of immunoprevalent antigens

Judkowski, Valeria A., Santos, Radleigh G., Bunying, Alcinette, Giulianotti, Marc A., Appel, Jon R., Pinilla, Clemencia

Journal:

Procedia in Vaccinology

Année:

2012

Langue:

english

Fichier:

PDF, 1.46 MB

english, 2012

48

High Throughput Synthesis of Peptide α-Thioesters Through the Use of “Volatilizable” Support

Li, Yangmei, Yu, Yongping, Giulianotti, Marc, Houghten, Richard A.

Journal:

Journal of Combinatorial Chemistry

Année:

2008

Langue:

english

Fichier:

PDF, 294 KB

english, 2008

49

Chemoinformatic Analysis of Combinatorial Libraries, Drugs, Natural Products, and Molecular Libraries Small Molecule Repository

Singh, Narender, Guha, Rajarshi, Giulianotti, Marc A., Pinilla, Clemencia, Houghten, Richard A., Medina-Franco, Jose L.

Journal:

Journal of Chemical Information and Modeling

Année:

2009

Langue:

english

Fichier:

PDF, 647 KB

english, 2009

50

Characterization of Activity Landscapes Using 2D and 3D Similarity Methods: Consensus Activity Cliffs

Medina-Franco, Jose L., Martínez-Mayorga, Karina, Bender, Andreas, Marín, Ray M., Giulianotti, Marc A., Pinilla, Clemencia, Houghten, Richard A.

Journal:

Journal of Chemical Information and Modeling

Année:

2009

Langue:

english

Fichier:

PDF, 950 KB

english, 2009